Vanilla cupcakes on and around a raised platter.

Vanilla Cupcakes

Made with buttermilk and topped with cream cheese frosting, these are the most luscious vanilla cupcakes. 

Servings: 24 cupcakes
Prep Time: 20 Minutes
Cook Time: 20 Minutes
Total Time: 45 Minutes, plus time to cool the cupcakes

Ingredients

For the Cupcakes

  • 1 cup buttermilk (see note)
  • 4 large eggs
  • 2 teaspoons vanilla extract
  • 2¾ cups cake flour, spooned into measuring cup and leveled-off (see note)
  • 2 cups sugar
  • Heaping ½ teaspoon salt
  • ½ teaspoon baking soda
  • 2 sticks (1 cup) unsalted butter, softened, plus more for greasing the pans
  • Cream cheese frosting or rich chocolate buttercream

Instructions

  1. Preheat the oven to 350° and set an oven rack in the middle position. Line two 12-cup muffin pans with paper liners. Lightly grease the top of the muffin pans with butter so the cupcake tops don't stick.
  2. In a medium bowl, whisk together the buttermilk, eggs, and vanilla. Set aside. (Note that the mixture will start to look curdled as it sits; that's okay.)
  3. In the bowl of an electric mixer fitted with the paddle attachment or beaters, combine the flour, sugar, baking soda, and salt. Beat on low speed for 30 seconds to combine. Add the soft butter and half of the buttermilk mixture and mix on low speed until moistened but still a little crumbly, about 1 minute. With the mixer running on low, gradually add the remaining buttermilk mixture, then increase the speed to medium and mix for three minutes, stopping once to scrape down the sides and bottom of the bowl with a rubber spatula. The batter should look pale and creamy. Scrape down the sides and bottom of the bowl again, making sure the batter is evenly mixed.
  4. Spoon the batter evenly into the prepared muffin pans, filling the cups almost full. Bake for 20 to 23 minutes, switching the pans from top to bottom and back to front midway through. Remove from the oven when the cupcakes are set, lightly golden, and a toothpick inserted into the center of a cupcake comes out clean (note that one pan may finish cooking before the other). Cool in the pan for about 15 minutes, then transfer to a rack to cool completely. Frost the cupcakes and store in an airtight container until ready to serve. The cupcakes are best served fresh on the day they are made, but they will keep nicely for up to 2 days.
  5. Note: If you’d like to make your own buttermilk, check out the easy method here.
  6. Note: Cake flour gives the cupcakes a fine texture. All-purpose flour can be substituted, but the cupcakes will be a bit heavier. To make your own cake flour, you can whisk together 2½ cups all-purpose flour and ¼ cup cornstarch.
  7. Freezer-Friendly Instructions: The cupcakes can be frozen without the frosting for up to 3 months. Let them cool completely, wrap them individually in plastic wrap, and then in foil. Thaw overnight on the countertop before serving. (Wait until the cupcakes are defrosted to ice them.)

Nutrition Information

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  • Serving size: 1 cupcake
  • Calories: 379
  • Fat: 19 g
  • Saturated fat: 12 g
  • Carbohydrates: 49 g
  • Sugar: 37 g
  • Protein: 4 g
  • Sodium: 155 mg
  • Cholesterol: 83 mg